Efficacy Analysis of the Serum Base: Sodium Hyaluronate (<100 kDa)

➢ Sodium Hyaluronate (<100 kDa): High-Quality Short-Chain Hyaluronic Acid

Sodium Hyaluronate is the sodium salt form of hyaluronic acid. Based on molecular weight, hyaluronic acid can be categorized into high molecular weight (>1000 kDa), medium molecular weight (100–1000 kDa), and low molecular weight (<100 kDa) variants. The low molecular weight form (<100 kDa) is commonly referred to as short-chain hyaluronic acid, which offers several unique advantages. The main benefits are outlined below:

1) Enhanced Skin Penetration

Due to its smaller molecular size, short-chain hyaluronic acid can more readily penetrate into the deeper layers of the skin. This enables it not only to form a moisturizing barrier on the skin’s surface but also to deliver hydration deep into the dermis, providing comprehensive and long-lasting moisturization from within.

2) Accelerated Skin Repair

Research has shown that short-chain hyaluronic acid promotes skin regeneration and wound healing. It stimulates the proliferation of skin cells, expedites the healing process, and may reduce the formation of scars. These properties are crucial for improving skin quality and maintaining a healthy skin condition.

3) Improved Skin Elasticity

By delivering deep hydration, short-chain hyaluronic acid helps enhance the skin's elasticity and firmness. It boosts cellular hydration levels, resulting in plumper-looking skin and a visible reduction in fine lines and wrinkles.

4) Anti-Aging Effects

The anti-aging benefits of short-chain hyaluronic acid stem primarily from its ability to provide deep moisture and support skin repair. Maintaining optimal hydration is key to preventing signs of aging, and the intense hydration provided by short-chain HA helps preserve a youthful, radiant appearance.

5) Strengthened Skin Barrier Function

While hyaluronic acid is widely recognized as an excellent moisturizer, short-chain hyaluronic acid also plays a role in reinforcing the skin’s natural barrier. By preserving moisture balance and overall skin health, it enhances the skin’s ability to resist external aggressors, such as irritants and environmental pollutants.

Thanks to its superior skin penetration, regenerative properties, elasticity-boosting effects, anti-aging potential, and barrier-strengthening benefits, short-chain hyaluronic acid (<100 kDa) is highly regarded in skincare and cosmetic formulations. These attributes make it an ideal active ingredient for high-performance moisturizers and anti-aging treatments.